Probing the origin of dihydrofolate reductase inhibition via proteochemometric modeling

Author:

Hariri Safoura1,Ghasemi Jahan B.2ORCID,Shirini Farhad13,Rasti Behnam4

Affiliation:

1. Department of Chemistry, University Campus 2; University of Guilan; Rasht Iran

2. Faculty of Chemistry; University of Tehran; Tehran Iran

3. Department of Chemistry, Faculty of Sciences; University of Guilan; Rasht Iran

4. Department of Microbiology, Faculty of Basic Sciences, Lahijan Branch; Islamic Azad University (IAU); Lahijan Guilan Iran

Publisher

Wiley

Subject

Applied Mathematics,Analytical Chemistry

Reference69 articles.

1. Cancer chemotherapy: targeting folic acid synthesis;Hagner;Cancer Manag Res,2010

2. DNA and RNA synthesis: antifolates;Kompis;Chem Rev,2005

3. Enhanced degradation of dihydrofolate reductase through inhibition of NAD kinase by nicotinamide analogs;Hsieh;Mol Pharmacol,2013

4. Pyrimido-pyrimidines: a novel class of Dihydrofolate reductase inhibitors;Banjanac;FTB,2009

5. Towards new antifolates targeting eukaryotic opportunistic infections;Liu;Eukaryot Cell,2009

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