Safety, Pharmacokinetics, and Biomarkers of an Amorphous Solid Dispersion of Genistein, a Radioprotectant, in Healthy Volunteers
Author:
Affiliation:
1. Humanetics Corporation Minneapolis Minnesota USA
2. Medical Monitoring Consultancy LLC St. Paul Minnesota USA
Publisher
Wiley
Subject
Pharmacology (medical),Pharmaceutical Science
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpdd.1188
Reference37 articles.
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2. Genistein Protects Against Biomarkers of Delayed Lung Sequelae in Mice Surviving High-Dose Total Body Irradiation
3. Radioprotection by the soy isoflavone genistein.
4. Mechanism and therapeutic window of a genistein nanosuspension to protect against hematopoietic-acute radiation syndrome
5. Genistein treatment protects mice from ionizing radiation injury
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1. BIO 300 Attenuates Whole Blood Transcriptome Changes in Mice Exposed to Total-Body Radiation;International Journal of Molecular Sciences;2024-08-13
2. Solid Dispersions of Genistein via Solvent Rotary Evaporation for Improving Solubility, Bioavailability, and Amelioration Effect in HFD-Induced Obesity Mice;Pharmaceutics;2024-02-22
3. Exploring Natural Products as Radioprotective Agents for Cancer Therapy: Mechanisms, Challenges, and Opportunities;Cancers;2023-07-12
4. Genistein: a promising modulator of apoptosis and survival signaling in cancer;Naunyn-Schmiedeberg's Archives of Pharmacology;2023-06-10
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