Caprylic acid-induced impurity precipitation from protein A capture column elution pool to enable a two-chromatography-step process for monoclonal antibody purification
Author:
Affiliation:
1. Biologics Development Dept.; Bristol-Myers Squibb; Bloomsbury NJ 08804
Publisher
Wiley
Subject
Biotechnology
Reference28 articles.
1. Bioseparation in antibody manufacturing: the good, the bad and the ugly;Gottschalk;Biotechnol Prog,2008
2. Protein A chromatography for antibody purification;Hober;J Chromatogr B,2007
3. Future of antibody purification;Low;J Chromatogr B,2007
4. Downsteam processing of monoclonal antibodies-Application of platform approaches;Shukla;J Chromatogr B,2007
5. Mechanism of precipitation of proteins by polyethylene glycols;Atha;J Biol Chem,1981
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