Tuneable resolution as a systems biology approach for multi-scale, multi-compartment computational models

Author:

Kirschner Denise E.1,Hunt C. Anthony2,Marino Simeone1,Fallahi-Sichani Mohammad3,Linderman Jennifer J.4

Affiliation:

1. Department of Microbiology and Immunology; University of Michigan Medical School; Ann Arbor MI USA

2. Department of Bioengineering and Therapeutic Sciences; University of California; San Francisco CA USA

3. Department of Systems Biology; Harvard Medical School; Boston MA USA

4. Department of Chemical Engineering; University of Michigan; Ann Arbor MI USA

Funder

NIH

Publisher

Wiley

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Medicine (miscellaneous)

Reference106 articles.

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2. Thinking again about biological mechanisms;Darden;Philos Sci,2008

3. Models and mechanisms in psychological explanation;Weiskopf;Synthese,2011

4. When mechanistic models explain;Craver;Synthese,2006

5. Interweaving categories: styles, paradigms, and models;Winther;Stud Hist Philos Sci A,2012

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