Synthesis and evaluation of 2‐(4‐[4‐acetylpiperazine‐1‐carbonyl] phenyl)‐ 1H ‐benzo[d]imidazole‐4‐carboxamide derivatives as potential PARP ‐1 inhibitors and preliminary study on structure‐activity relationship
Author:
Affiliation:
1. Institute of Pharmacy and Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study University of South China Changsheng West Road 28# Hengyang 421001 China
Funder
Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study
Publisher
Wiley
Subject
Drug Discovery
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ddr.21843
Reference24 articles.
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1. An overview of compound properties, multiparameter optimization, and computational drug design methods for PARP-1 inhibitor drugs;European Journal of Medicinal Chemistry;2023-04
2. Design, synthesis, and evaluation of 1H‐benzo[d]imidazole‐4‐carboxamide PARP‐1 inhibitors using different saturated nitrogen‐contained heterocycle as linker group;Chemical Biology & Drug Design;2023-03-05
3. Recent Progress in the Research on Benzimidazole PARP-1 Inhibitors;Mini-Reviews in Medicinal Chemistry;2022-10
4. Recent advances in structural types and medicinal chemistry of PARP-1 inhibitors;Medicinal Chemistry Research;2022-06-10
5. Recent progress of research on anti‐tumor agents using benzimidazole as the structure unit;Chemical Biology & Drug Design;2022-02-09
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