High heparin content surface-modified polyurethane discs promote rapid and stable angiogenesis in full thickness skin defects through VEGF immobilization

Author:

McLuckie Michelle12,Schmidt Christian A.3,Oosthuysen Anel4,Sanchez-Macedo Nadia12,Merker Hannes1,Bezuidenhout Deon4,Hoerstrup Simon P.56,Lindenblatt Nicole16

Affiliation:

1. Clinic for Plastic Surgery and Hand Surgery; University Hospital Zurich; Zurich Switzerland

2. Division of Surgical Research; University Hospital Zurich; Zurich Switzerland

3. Clinic for Cardiovascular Surgery; University Hospital Zurich; Zurich Switzerland

4. Division of Cardiothoracic Surgery; University of Cape Town; Cape Town South Africa

5. Institute for Regenerative Medicine, University of Zurich; Zurich Switzerland

6. Zurich Center for Integrative Human Physiology (ZIHP); Zurich Switzerland

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Wiley

Subject

Metals and Alloys,Biomedical Engineering,Biomaterials,Ceramics and Composites

Reference33 articles.

1. Angiogenesis in tissue engineering: Breathing life into constructed tissue substitutes;Laschke;Tissue Eng,2006

2. Scaffold vascularization: A challenge for three-dimensional tissue engineering;Bramfeldt;Curr Med Chem,2010

3. Experimental approaches to vascularisation within tissue engineering constructs, Journal of Biomaterials Science;Sarker;Polym Ed,2015

4. Vascularization in tissue engineering: Angiogenesis versus inosculation;Laschke;Eur Surg Res,2012

5. Prevascularization in tissue engineering: Current concepts and future directions;Laschke;Biotechnol Adv,2016

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