QSAR and Pharmacophores for Drugs Involved in hERG Blockage
Author:
Publisher
Wiley
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/9783527621460.ch5
Reference44 articles.
1. Molecular and Cellular Mechanisms of Cardiac Arrhythmias
2. hERG potassium channels and cardiac arrhythmia
3. The impact of drug-induced QT interval prolongation on drug discovery and development
4. Organising evidence on QT prolongation and occurrence of Torsades de Pointes with non-antiarrhythmic drugs: a call for consensus
5. Drug-Induced Torsades de Pointes and Implications for Drug Development
Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. In silico prediction of hERG inhibition;Future Medicinal Chemistry;2015-04
2. QSAR Modeling and Data Mining Link Torsades de Pointes Risk to the Interplay of Extent of Metabolism, Active Transport, and hERG Liability;Molecular Pharmaceutics;2012-07-13
3. hERG-related drug toxicity and models for predicting hERG liability and QT prolongation;Expert Opinion on Drug Metabolism & Toxicology;2009-07-03
4. Combining Cluster Analysis, Feature Selection and Multiple Support Vector Machine Models for the Identification of Human Ether-a-go-go Related Gene Channel Blocking Compounds;Chemical Biology & Drug Design;2009-01
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