Design, synthesis and biological evaluation of deuterated nintedanib for improving pharmacokinetic properties-Reference-Cited by-同舟云学术

Design, synthesis and biological evaluation of deuterated nintedanib for improving pharmacokinetic properties

Published:2015-05-26 Issue:7 Volume:58 Page:308-312
ISSN:0362-4803
Container-title:Journal of Labelled Compounds and Radiopharmaceuticals
language:en
Short-container-title:J. Label Compd. Radiopharm

Author:

Xu Ruixue¹,Zhan Miao¹,Peng Lingling¹,Pang Xuehai²,Yang Jun¹,Zhang Tao¹,Jiang Hongxia¹,Zhao Lifeng¹,Chen Yuanwei¹²

Affiliation:

1. State Key Laboratory of Biotherapy and Cancer Center, West China Hospital; Sichuan University, and Collaborative Innovation Center for Biotherapy; Chengdu 610041 China

2. Hinova Pharmaceuticals Inc; Suite 801, Building C1, #88 South KeYuan Road, Chengdu Tianfu Life Science Park Chengdu 610041 China

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Reference31 articles.

1. BIBF 1120: Triple Angiokinase Inhibitor with Sustained Receptor Blockade and Good Antitumor Efficacy

2. Design, Synthesis, and Evaluation of Indolinones as Triple Angiokinase Inhibitors and the Discovery of a Highly Specific 6-Methoxycarbonyl-Substituted Indolinone (BIBF 1120)

3. Angiogenesis in health and disease

4. Angiogenesis as a therapeutic target

5. Role of the Vascular Endothelial Growth Factor Pathway in Tumor Growth and Angiogenesis

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