Increased Systemic Exposure and Stronger Cardiovascular and Metabolic Adverse Reactions to Fenoterol in Individuals with HeritableOCT1Deficiency

Author:

Tzvetkov Mladen V.1,Matthaei Johannes1,Pojar Sherin1,Faltraco Frank,Vogler Sabrina1,Prukop Thomas1,Seitz Tina1,Brockmöller Jürgen1

Affiliation:

1. Institute for Clinical Pharmacology; University Medical Center Göttingen; Göttingen Germany

Funder

German Research Foundation

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference37 articles.

1. Prescribed fenoterol and death from asthma in New Zealand, 1981-83: case-control study;Crane;Lancet,1989

2. End of the New Zealand asthma mortality epidemic;Pearce;Lancet,1995

3. The use of beta-agonists and the risk of death and near death from asthma;Spitzer;N. Engl. J. Med.,1992

4. A comparison of the cardiovascular and metabolic effects of formoterol, salbutamol and fenoterol;Bremner;Eur. Respir. J.,1993

5. Gellermann , H.J. Hoffmann , H. Dear Doctor Letter (Rote-Hand-Brief) on short-acting beta-agonists/beta 2-sympathomimetic agents (SABAs) for obstetric indications - including Partusisten® (fenoterol): restrictions of indication https://www.bfarm.de/SharedDocs/Risikoinformationen/Pharmakovigilanz/EN/RHB/2013/rhb-partusisten.html 2013

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