Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2-Reference-Cited by-同舟云学术

Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2

Published:2023-06-08 Issue:7 Volume:30 Page:1001-1011
ISSN:1545-9993
Container-title:Nature Structural & Molecular Biology
language:en
Short-container-title:Nat Struct Mol Biol

Author:

Suo Yang^ORCID,Wright Nicholas J.^ORCID,Guterres Hugo^ORCID,Fedor Justin G.^ORCID,Butay Kevin John^ORCID,Borgnia Mario J.^ORCID,Im Wonpil^ORCID,Lee Seok-Yong^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Structural Biology

Link

https://www.nature.com/articles/s41594-023-01017-4.pdf

Reference88 articles.

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2. Chen, L. et al. OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin. Proc. Natl Acad. Sci. USA 111, 9983–9988 (2014).

3. Cheung, K. W. K. et al. The effect of uremic solutes on the organic cation transporter 2. J. Pharm. Sci. 106, 2551–2557 (2017).

4. Boxberger, K. H., Hagenbuch, B. & Lampe, J. N. Common drugs inhibit human organic cation transporter 1 (OCT1)-mediated neurotransmitter uptake. Drug Metab. Dispos. 42, 990–995 (2014).

5. Bacq, A. et al. Organic cation transporter 2 controls brain norepinephrine and serotonin clearance and antidepressant response. Mol. Psychiatry 17, 926–939 (2012).

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