Microscopic visualization of virus removal by dedicated filters used in biopharmaceutical processing: Impact of membrane structure and localization of captured virus particles

Author:

Adan‐Kubo Jun1ORCID,Tsujikawa Muneo1,Takahashi Kadue1,Hongo‐Hirasaki Tomoko2,Sakai Kaoru1

Affiliation:

1. Central Research LaboratoryJapanese Blood Products Organization Kobe Hyogo Prefecture Japan

2. Technology Development Department, Bioprocess DivisionAsahi Kasei Medical Co. Ltd. Nobeoka Miyazaki Prefecture Japan

Funder

Ministry of Education, Culture, Sports, Science and Technology

Publisher

Wiley

Subject

Biotechnology

Reference34 articles.

1. Emerging viral infections—a potential threat for blood supply in the 21st century;Mendoza C;AIDS Rev,2012

2. Inactivation of parvovirus B19 by liquid heating incorporated in the manufacturing process of human intravenous immunoglobulin preparations

3. Variability of parvovirus B19 to inactivation by liquid heating in plasma products

4. Hepatitis E virus and the safety of plasma products: investigations into the reduction capacity of manufacturing processes

5. EMA/CHMP/BWP/706271/2010. EMA/CHMP. Guideline: Guideline on plasma‐derived medicinal products. July 21 2011.

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