Cationic Solution and Solid‐State Emitters – Robust Imaging Agents for Cells, Bacteria, and Protists

Author:

Dubbert Justin1,Höing Alexander2,Graupner Nadine3,Rajter Ľubomír3,Dunthorn Micah4,Knauer Shirley K.2,Galstyan Anzhela5,Rizzo Fabio67ORCID,Voskuhl Jens1ORCID

Affiliation:

1. Faculty of Chemistry (Organic Chemistry) Center of Medical Biotechnology (ZMB) and Center for NanoIntegration (CENIDE) University of Duisburg-Essen Universitätsstrasse 7 45117 Essen Germany

2. Institute for Molecular Biology II Center for Medical Biotechnology (ZMB) University of Duisburg-Essen Universitätsstrasse 5 45117 Essen Germany

3. Faculty of Biology, Eukaryotic Microbiology, Phycology University of Duisburg-Essen Universitätsstrasse 5 45141 Essen Germany

4. Natural History Museum University of Oslo N-0318 Oslo Norway

5. Faculty of Chemistry (Analytical Chemistry) Center for NanoIntegration (CENIDE) and Center for Water and Environment Research (ZWU) University of Duisburg-Essen Universitätsstrasse 5 45117 Essen Germany

6. Center for Soft Nanoscience (SoN) Westfälische Wilhelms-Universität Münster Busso-Peus-Str. 10 48149 Münster Germany

7. Institute of Chemical Science and Technologies “G. Natta” (SCITEC) National Research Council (CNR) Via G. Fantoli 16/15 20138 Milan Italy).

Abstract

AbstractA library of eight different cationic emitters with emission properties in solution and in solid‐state (solution and solid‐state emitters – SSSE) is presented. These compounds, bearing either ammonium or pyridinium groups, have been investigated regarding their photophysical properties as well as their potential application in biological imaging. Besides high quantum yields as well as a high degree of stability during the imaging process, it was additionally revealed that a broad range of biological targets can be addressed, such as different bacterial strains, human cells as well as protists. The reported SSSE approach employing the mentioned robust emitters for biological imaging, will contribute to a rapid and facile way to design and apply affordable emitters with outstanding properties. Additionally, these emitters will overcome the drawbacks of classical luminophores and agents featuring well‐known aggregation‐induced emission (AIE) or aggregation‐caused quenching (ACQ) properties.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Reference72 articles.

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