Deoxyestrone-based lipofection agents with solution- and solid-state emission properties-Reference-Cited by-同舟云学术

Deoxyestrone-based lipofection agents with solution- and solid-state emission properties

Published:2023 Issue:28 Volume:21 Page:5762-5767
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Huber Alexander¹,Koch Johannes²,Rudolph Kevin¹,Höing Alexander³^ORCID,Rizzo Fabio⁴⁵^ORCID,Knauer Shirley K.³^ORCID,Voskuhl Jens¹^ORCID

Affiliation:

1. Faculty of Chemistry (Organic Chemistry), Center of Medical Biotechnology (ZMB) and Center for NanoIntegration (CENIDE), University of Duisburg-Essen, Universitätsstrasse 7, 45117 Essen, Germany

2. Center of Medical Biotechnology (ZMB), University of Duisburg Essen, Universitätsstraße 2, 45141 Essen, Germany

3. Department of Molecular Biology II, Center of Medical Biotechnology (ZMB), University of Duisburg Essen, Universitätsstraße 2, 45141 Essen, Germany

4. Center for Soft Nanoscience (SoN), Westfälische Wilhelms-Universität Münster, Busso-Peus-Straße 10, 48149 Münster, Germany

5. Institute of Chemical Science and Technologies “G. Natta” (SCITEC), National Research Council (CNR), Via G. Fantoli 16/15, 20138 Milan, Italy

Abstract

The first class of solution and solid-state emitters (SSSE) capable of mediating gene transfection of different cell lines is reported. These amphiphiles can self-assemble in presence of DNA, forming luminescent lipoplexes that feature low toxicity.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00656E

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