Metabolism study for CUMYL-4CN-BINACA in human hepatocytes and authentic urine specimens: Free cyanide is formed during the main metabolic pathway-Reference-Cited by-同舟云学术

Metabolism study for CUMYL-4CN-BINACA in human hepatocytes and authentic urine specimens: Free cyanide is formed during the main metabolic pathway

Published:2018-04-16 Issue:8 Volume:10 Page:1270-1279
ISSN:1942-7603
Container-title:Drug Testing and Analysis
language:en
Short-container-title:Drug Test Anal

Author:

Åstrand Anna¹,Vikingsson Svante¹²,Lindstedt Daniel¹,Thelander Gunilla¹,Gréen Henrik¹²,Kronstrand Robert¹²^ORCID,Wohlfarth Ariane¹²^ORCID

Affiliation:

1. Department of Forensic Genetics and Forensic Toxicology; National Board of Forensic Medicine; Linköping Sweden

2. Division of Drug Research, Department of Medical Health Sciences; Linköping University; Linköping Sweden

Funder

Eurostars

Strategic Research Area in Forensic Sciences, Linköping

VINNOVA

Publisher

Wiley

Subject

Spectroscopy,Pharmaceutical Science,Environmental Chemistry,Analytical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/dta.2373/fullpdf

Reference15 articles.

1. European Monitoring Centre of Drugs and Drug Addiction Perspectives on Drugs: Synthetic cannabinoids in Europe 2017 http://www.emcdda.europa.eu/publications/pods/synthetic-cannabinoids

2. European Monitoring Centre of Drugs and Drug Addiction European Drug Report 2017: Trends and Developments 2017

3. European Monitoring Centre of Drugs and Drug Addiction EMCDDA-Europol Joint Report on a new psychoactive substance: 1-(4-cyanobutyl)-N-(2-phenylpropan-2-yl)indazole-3-carboxamide (CUMYL-4CN-BINACA) 2017 https://doi.org/10.2810/446879

4. Pharmacology of cumyl-carboxamide synthetic cannabinoid new psychoactive substances (NPS) CUMYL-BICA, CUMYL-PICA, CUMYL-5F-PICA, CUMYL-5F-PINACA, and their analogues;Longworth;ACS Chem Nerosci,2017

5. Nitrile-containing pharmaceuticals: Efficacious roles of the nitrile pharmacophore;Fleming;J Med Chem,2010

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