The potential of random forest and neural networks for biomass and recombinant protein modeling in Escherichia coli fed‐batch fermentations

Author:

Melcher Michael12,Scharl Theresa1,Spangl Bernhard12,Luchner Markus13,Cserjan Monika13,Bayer Karl13,Leisch Friedrich12,Striedner Gerald13

Affiliation:

1. Austrian Centre of Industrial Biotechnology, Graz, Austria

2. Institute of Applied Statistics and Computing, University of Natural Resources and Life Sciences, Vienna, Austria

3. Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria

Publisher

Wiley

Subject

Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine

Reference32 articles.

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2. International Conference on Harmonisation; guidance on Q9 Quality Risk Management; availability. Notice.;Food and Drug Administration, H. H. S.;Fed. Regist.,2006

3. International Conference on Harmonisation; guidance on Q10 Pharmaceutical Quality System; availability. Notice.;Food and Drug Administration H. H. S.;Fed. Regist.,2009

4. Food and Drug Administration H. H. S. Guidance for Industry: PAT – A Framework for Innovative Pharmaceutical Development Manufacturing and Quality Assurance 2004. http://www.fda.gov/downloads/Drugs/Guidances/ucm070305.pdf [Oct 13 2014].

5. Roadmap for implementation of quality by design (QbD) for biotechnology products

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