Cross‐Interaction Chromatography‐Based QSAR Model for Early‐Stage Screening to Facilitate Enhanced Developability of Monoclonal Antibody Therapeutics

Author:

Kizhedath Arathi1,Karlberg Micael1,Glassey Jarka1ORCID

Affiliation:

1. School of Engineering, Newcastle UniversityNewcastle upon Tyne NE17RU UK

Funder

H2020 Marie Sklodowska-Curie Actions

Publisher

Wiley

Subject

Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine

Reference64 articles.

1. EvaluatePharma®. World Preview 2016 Outlook to 2022. EvaluatePharma http://info.evaluategroup.com/rs/607‐YGS‐364/images/wp16.pdf(accessed: January 16 2017) 2016.

2. EvaluatePharma®. World Preview 2017 Outlook to 2022 10th ed. 2017.

3. EvaluatePharma®. World Preview 2018 Outlook to 2024 10th ed. 2018.

4. Solubility Challenges in High Concentration Monoclonal Antibody Formulations: Relationship with Amino Acid Sequence and Intermolecular Interactions

5. Use of In Vitro Assays to Assess Immunogenicity Risk of Antibody-Based Biotherapeutics

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