Non-specificity as the sticky problem in therapeutic antibody development
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Chemical Engineering,General Chemistry
Link
https://www.nature.com/articles/s41570-022-00438-x.pdf
Reference235 articles.
1. Goldberg, R. J. A theory of antibody–antigen reactions. I. Theory for reactions of multivalent antigen with bivalent and univalent antibody2. J. Am. Chem. Soc. 74, 5715–5725 (1952).
2. Goldberg, R. J. A theory of antibody–antigen reactions. II. theory for reactions of multivalent antigen with multivalent antibody. J. Am. Chem. Soc. 75, 3127–3131 (1953).
3. Boyden, S. V. Natural antibodies and the immune response. Adv. Immunol. 5, 1–28 (1966).
4. Padlan, E. A. Anatomy of the antibody molecule. Mol. Immunol. 31, 169–217 (1994).
5. Ehrlich, P. Die grundlagn der experimentellen chemotherapie. Angew. Chem. 23, 2–8 (1910). The first description of antibodies as ‘magic bullets’.
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