Single Copy Transgene Integration in a Transcriptionally Active Site for Recombinant Protein Synthesis-Reference-Cited by-同舟云学术

Single Copy Transgene Integration in a Transcriptionally Active Site for Recombinant Protein Synthesis

Published:2018-07-30 Issue:10 Volume:13 Page:1800226
ISSN:1860-6768
Container-title:Biotechnology Journal
language:en
Short-container-title:Biotechnol. J.

Author:

O'Brien Sofie A.¹,Lee Kyoungho¹,Fu Hsu-Yuan¹,Lee Zion¹,Le Tung S.¹,Stach Christopher S.²,McCann Meghan G.¹,Zhang Alicia Q.¹,Smanski Michael J.²,Somia Nikunj V.³,Hu Wei-Shou¹

Affiliation:

1. Department of Chemical Engineering and Materials Science; University of Minnesota; Minneapolis MN 55455-0132 USA

2. Department of Biochemistry, Molecular Biology, and Biophysics; University of Minnesota; Saint Paul MN 55108-6106 USA

3. Department of Genetics, Cell Biology, and Development; University of Minnesota; Minneapolis MN 55455-0465 USA

Funder

Minnesota Futures Grant

NIGMS Biotechnology Training Program

Vietnam Education Foundation (VEF)

Publisher

Wiley

Subject

Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/biot.201800226/fullpdf

Reference58 articles.

1. Recent advances in (therapeutic protein) drug development

2. CHO Quasispecies—Implications for Manufacturing Processes

3. Advancement in bioprocess technology: parallels between microbial natural products and cell culture biologics

4. Clonal variability within dihydrofolate reductase-mediated gene amplified Chinese hamster ovary cells: Stability in the absence of selective pressure

5. Road to precision: recombinase-based targeting technologies for genome engineering

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