Identification of thermostabilizing mutations for a membrane protein whose three-dimensional structure is unknown-Reference-Cited by-同舟云学术

Identification of thermostabilizing mutations for a membrane protein whose three-dimensional structure is unknown

Published:2016-11-14 Issue:4 Volume:38 Page:211-223
ISSN:0192-8651
Container-title:Journal of Computational Chemistry
language:en
Short-container-title:J. Comput. Chem.

Author:

Kajiwara Yuta¹,Yasuda Satoshi²³⁴,Takamuku Yuuki²,Murata Takeshi²³⁵,Kinoshita Masahiro⁴

Affiliation:

1. Department of Fundamental Energy Science, Graduate School of Energy Science; Kyoto University; Uji Kyoto 611-0011 Japan

2. Department of Chemistry, Graduate School of Science; Chiba University; 1-33 Yayoi-cho Inage Chiba 263-8522 Japan

3. Molecular Chirality Research Center; Chiba University; 1-33 Yayoi-cho Inage Chiba 263-8522 Japan

4. Laboratory for Complex Energy Processes Section, Institute of Advanced Energy; Kyoto University; Uji Kyoto 611-0011 Japan

5. JST, PRESTO; 1-33 Yayoi-cho Inage Chiba 263-8522 Japan

Funder

Koyanagi Foundation

ImPACT Program of Council for Science, Technology and Innovation (Cabinet Office, Government of Japan)

The Platform Project for Supporting in Drug Discovery and Life Science Research (Platform for Drug Discovery, Informatics, and Structural Life Science)

Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT)

Japan Agency for Medical Research and Development (AMED)

Publisher

Wiley

Subject

Computational Mathematics,General Chemistry

Reference40 articles.

1. How many membrane proteins are there?

2. Genome-wide analysis of integral membrane proteins from eubacterial, archaean, and eukaryotic organisms

3. Drug—target network

4. Changing single side-chains can greatly enhance the resistance of a membrane protein to irreversible inactivation

5. Building a Thermostable Membrane Protein

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