Synthesis of Unsymmetrical Squaramides as Allosteric GSK‐3β Inhibitors Promoting β‐Catenin‐Mediated Transcription of TCF/LEF in Retinal Pigment Epithelial Cells-Reference-Cited by-同舟云学术

Synthesis of Unsymmetrical Squaramides as Allosteric GSK‐3β Inhibitors Promoting β‐Catenin‐Mediated Transcription of TCF/LEF in Retinal Pigment Epithelial Cells

Published:2022-10-27 Issue:24 Volume:17 Page:
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Carullo Gabriele¹^ORCID,Bottoni Laura²,Pasquini Silvia³,Papa Alessandro²^ORCID,Contri Chiara⁴,Brogi Simone⁵^ORCID,Calderone Vincenzo⁵^ORCID,Orlandini Maurizio²,Gemma Sandra²,Varani Katia⁴,Butini Stefania²^ORCID,Galvagni Federico²,Vincenzi Fabrizio⁴,Campiani Giuseppe²^ORCID

Affiliation:

1. Department of Life Sciences University of Siena Via Aldo Moro 2 53100 Siena Italy

2. Department of Biotechnology Chemistry and Pharmacy University of Siena Via Aldo Moro 2 53100 Siena Italy

3. Department of Chemical, Pharmaceutical and Agricultural Sciences University of Ferrara Via Fossato di Mortara 17–19 44121 Ferrara Italy

4. Department of Translational Medicine University of Ferrara Via Fossato di Mortara 17–19 44121 Ferrara Italy

5. Department of Pharmacy University of Pisa Via Bonanno 6 56126 Pisa Italy

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202200456

Reference52 articles.

1. GSK-3 – at the crossroads of cell death and survival

2. Glycogen Synthase Kinase 3

3. GSK3β, a Master Kinase in the Regulation of Adult Stem Cell Behavior

4. Cytotoxicity and activation of the Wnt/beta-catenin pathway in mouse embryonic stem cells treated with four GSK3 inhibitors

5. Targeting the interaction of β-catenin and TCF/LEF transcription factors to inhibit oncogenic Wnt signaling

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