An Experimental Toolbox for Structure‐Based Hit Discovery for P . aeruginosa FabF, a Promising Target for Antibiotics-Reference-Cited by-同舟云学术

An Experimental Toolbox for Structure‐Based Hit Discovery for P . aeruginosa FabF, a Promising Target for Antibiotics

Published:2021-08-06 Issue:17 Volume:16 Page:2715-2726
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Espeland Ludvik Olai¹²^ORCID,Georgiou Charis¹^ORCID,Klein Raphael¹³^ORCID,Bhukya Hemalatha⁴,Haug Bengt Erik²^ORCID,Underhaug Jarl²^ORCID,Mainkar Prathama S.⁴^ORCID,Brenk Ruth¹^ORCID

Affiliation:

1. Department of Biomedicine University of Bergen Jonas Lies Vei 91 5020 Bergen Norway

2. Department of Chemistry University of Bergen Allégaten 41 5007 Bergen Norway

3. Institute of Pharmacy and Biochemistry Johannes Gutenberg University Staudingerweg 5 55128 Mainz Germany

4. Department of Organic Synthesis & Process Chemistry CSIR-Indian Institute of Chemical Technology Tarnaka Hyderabad 500007 India

Funder

Norges Forskningsråd

Indian Council of Medical Research

Universitetet i Bergen

Bergens Forskningsstiftelse

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202100302

Reference59 articles.

1. Antibacterial drug discovery in the resistance era

2. Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

3. Critical analysis of antibacterial agents in clinical development

4. Bacterial fatty acid metabolism in modern antibiotic discovery

5. Structure and molecular organization of mammalian fatty acid synthase

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