Targeting the S100A2‐p53 Interaction with a Series of 3,5‐ Bis (trifluoromethyl)benzene Sulfonamides: Synthesis and Cytotoxicity-Reference-Cited by-同舟云学术

Targeting the S100A2‐p53 Interaction with a Series of 3,5‐ Bis (trifluoromethyl)benzene Sulfonamides: Synthesis and Cytotoxicity

Published:2021-07-13 Issue:18 Volume:16 Page:2851-2863
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Sun Jufeng¹²^ORCID,Ambrus Joey I.¹,Russell Cecilia C.¹,Baker Jennifer R.¹^ORCID,Cossar Peter J.¹^ORCID,Pirinen Melanie J.³^ORCID,Sakoff Jennette A.⁴^ORCID,Scarlett Christopher J.³^ORCID,McCluskey Adam¹^ORCID

Affiliation:

1. Chemistry School of Environmental & Life Sciences The University of Newcastle University Drive Callaghan NSW 2308 Australia

2. Medicinal Chemistry School of Pharmacy Binzhou Medical University Yantai 264003 China

3. School of Environmental & Life Sciences The University of Newcastle Ourimbah NSW 2258 Australia

4. Experimental Therapeutics Group, Department of Medical Oncology Calvary Mater Newcastle Hospital Edith Street Waratah NSW 2298 Australia

Funder

Australian Cancer Research Foundation

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000949

Reference25 articles.

1. Concepts to Target MYC in Pancreatic Cancer

2. Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

3. https://www.canceraustralia.gov.au/publications-and-resources/cancer-australia-publications/pancreatic-cancer-fact-sheet. Types of Pancreatic Cancer Fact Sheet.2014 No. June 2014.

4. Isolation of a new member of the S100 protein family: amino acid sequence, tissue, and subcellular distribution.

5. S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature)

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3. 3,5-Bis(trifluoromethyl)phenylsulfonamides, a novel pancreatic cancer active lead. Investigation of the terminal aromatic moiety;Bioorganic & Medicinal Chemistry Letters;2022-04