Pentathiepins: A Novel Class of Glutathione Peroxidase 1 Inhibitors that Induce Oxidative Stress, Loss of Mitochondrial Membrane Potential and Apoptosis in Human Cancer Cells-Reference-Cited by-同舟云学术

Pentathiepins: A Novel Class of Glutathione Peroxidase 1 Inhibitors that Induce Oxidative Stress, Loss of Mitochondrial Membrane Potential and Apoptosis in Human Cancer Cells

Published:2020-05-06 Issue:16 Volume:15 Page:1515-1528
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Behnisch‐Cornwell Steven¹,Bandaru Siva Sankar Murthy²,Napierkowski Martin¹,Wolff Lisa¹,Zubair Muhammad²,Urbainsky Claudia³,Lillig Christopher³,Schulzke Carola²,Bednarski Patrick J.¹^ORCID

Affiliation:

1. Pharmazeutische/Medizinische ChemieInstitut für PharmazieUniversität Greifswald 17489 Greifswald Germany

2. Bioanorganische ChemieInstitut für BiochemieUniversität Greifswald 17489 Greifswald Germany

3. Institut für Medizinische Biochemie und Molekulare BiologieUniversitätsmedizinUniversität Greifswald 17475 Greifswald Germany

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000160

Reference61 articles.

1. Glutathione Peroxidase-1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities

2. Purification and properties of a recombinant sulfur analog of murine selenium-glutathione peroxidase

3. Catalytic mechanisms and specificities of glutathione peroxidases: Variations of a basic scheme

5. Mice Deficient in Cellular Glutathione Peroxidase Develop Normally and Show No Increased Sensitivity to Hyperoxia

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