Evaluation of Water‐Soluble Mannich Base Prodrugs of 2,3,4,5‐Tetrahydroazepino[4,3‐ b ]indol‐1(6 H )‐one as Multitarget‐Directed Agents for Alzheimer's Disease-Reference-Cited by-同舟云学术

Evaluation of Water‐Soluble Mannich Base Prodrugs of 2,3,4,5‐Tetrahydroazepino[4,3‐ b ]indol‐1(6 H )‐one as Multitarget‐Directed Agents for Alzheimer's Disease

Published:2020-12-04 Issue:3 Volume:16 Page:589-598
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Purgatorio Rosa¹,Candia Modesto¹,Catto Marco¹,Rullo Mariagrazia¹,Pisani Leonardo¹,Denora Nunzio¹,Carrieri Antonio¹,Nevskaya Alisa A.²,Voskressensky Leonid G.²,Altomare Cosimo D.¹

Affiliation:

1. Department of Pharmacy-Drug-Sciences University of Bari Aldo Moro Via E. Orabona 4 70125 Bari Italy

2. Organic Chemistry Department RUDN University Miklukho-Maklai St. 6 Moscow 117198 Russia

Funder

Ministry of Education and Science of the Russian Federation

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000583

Reference37 articles.

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2. A review on Alzheimer's disease pathophysiology and its management: an update

3. Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade

4. Pharmacotherapy of Alzheimer’s disease: current and future trends

5. Conjugates of γ-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease

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