Antimicrobial Peptide Mimetics Based on a Diphenylacetylene Scaffold: Synthesis, Conformational Analysis, and Activity-Reference-Cited by-同舟云学术

Antimicrobial Peptide Mimetics Based on a Diphenylacetylene Scaffold: Synthesis, Conformational Analysis, and Activity

Published:2020-09-15 Issue:20 Volume:15 Page:1932-1939
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Peacock Hayden¹²³^ORCID,Henriques Sónia Troeira²⁴^ORCID,Benfield Aurélie H.²⁴^ORCID,Elliott Alysha G.²^ORCID,Luo Jinghui³⁵^ORCID,Luccarelli James³⁶^ORCID,Nagano Masanobu¹,Craik David J.²^ORCID,Hamilton Andrew D.⁷³

Affiliation:

1. Department of Chemistry The University of Tokyo 7-3-1 Hongo, Bunkyo-ku Tokyo 113-0033 Japan

2. Institute for Molecular Bioscience The University of Queensland Brisbane QLD 4072 Australia

3. Chemistry Research Laboratory The University of Oxford 12 Mansfield Road Oxford OX1 3TA UK

4. School of Biomedical Sciences Institute of Health & Biomedical Innovation and Translational Research Institute Queensland University of Technology Brisbane QLD, 4102 Australia

5. Laboratory of Nanoscale Biology Paul Scherrer Institute 5232 Villigen Switzerland

6. Department of Psychiatry Massachusetts General Hospital Boston MA 02114 USA

7. Department of Chemistry New York University New York NY 10003 USA

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000474

Reference41 articles.

1. Targeting bacterial membrane function: an underexploited mechanism for treating persistent infections

2. Antimicrobial peptides (AMPs): Ancient compounds that represent novel weapons in the fight against bacteria

3. The Vast Structural Diversity of Antimicrobial Peptides

4. Host defense antimicrobial peptides as antibiotics: design and application strategies

5. Membrane-targeting antibiotics: recent developments outside the peptide space

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