Andrographolide Derivatives Target the KEAP1/NRF2 Axis and Possess Potent Anti‐SARS‐CoV‐2 Activity

Author:

Schulte Bianca1,König Maria2,Escher Beate I.23ORCID,Wittenburg Sophie4ORCID,Proj Matic5ORCID,Wolf Valentina4,Lemke Carina4,Schnakenburg Gregor6ORCID,Sosič Izidor5ORCID,Streeck Hendrik17ORCID,Müller Christa E.4ORCID,Gütschow Michael4ORCID,Steinebach Christian4ORCID

Affiliation:

1. Institute of Virology University Hospital Bonn Venusberg-Campus 1 53127 Bonn Germany

2. Helmholtz Centre for Environmental Research–UFZ Permoserstraße 15 04318 Leipzig Germany

3. Center for Applied Geoscience Eberhard Karls University Tübingen 72076 Tübingen Germany

4. Pharmaceutical Institute University of Bonn An der Immenburg 4 53121 Bonn Germany

5. Faculty of Pharmacy University of Ljubljana Aškerčeva cesta 7 1000 Ljubljana Slovenia

6. Institute of Inorganic Chemistry University of Bonn Gerhard-Domagk-Str. 1 53121 Bonn Germany

7. German Center for Infection Research (DZIF) Partner Site Bonn-Cologne Germany

Funder

Volkswagen Foundation

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

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