Andrographolide protects chondrocytes from oxidative stress injury by activation of the Keap1–Nrf2–Are signaling pathway

Author:

Li Bo123,Jiang Tongmeng1234ORCID,Liu Hui123,Miao Zhikang124,Fang Depeng123,Zheng Li1234ORCID,Zhao Jinmin1234ORCID

Affiliation:

1. Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration The First Affiliated Hospital of Guangxi Medical University Nanning China

2. Guangxi Collaborative Innovation Center for Biomedicine The First Affiliated Hospital of Guangxi Medical University Nanning China

3. Department of Orthopaedics Trauma and Hand Surgery The First Affiliated Hospital of Guangxi Medical University Nanning China

4. Guangxi Key Laboratory of Regenerative Medicine The First Affiliated Hospital of Guangxi Medical University Nanning China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Reference39 articles.

1. The transcription factor Nrf2 promotes survival by enhancing the expression of uncoupling protein 3 under conditions of oxidative stress

2. A rapid and sensitive method for the quantitation of microgram quantities of protein using the principle of protein dye binding;Bradford M. M.;Analytical Biochemistry,1976

3. Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial

4. Andrographolide activates Nrf2 to inhibit ethanol‐induced oxidative stress damage in hepatic cells;Cao H.;Genomics & Applied Biology,2016

5. Intracellular oxidative activation in synovial fluid neutrophils from patients with rheumatoid arthritis but not from other arthritis patients;Cedergren J.;Journal of Rheumatology,2007

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