Endometrial breakdown with sustained progesterone release involves NF-κB-mediated functional progesterone withdrawal in a mouse implant model
Author:
Affiliation:
1. Hebei Key Laboratory of Chinese Medicine Research on Cardio-Cerebrovascular Disease; Hebei University of Chinese Medicine; Shijiazhuang P. R. China
2. National Research Institute for Family Planning; Beijing P. R. China
Funder
National Nature Science Foundation of China
Nature Fund of Hebei Province, P. R. China
Publisher
Wiley
Subject
Cell Biology,Developmental Biology,Genetics
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4. Up-regulation of the progesterone receptor (PR)-C isoform in laboring myometrium by activation of nuclear factor-kappaB may contribute to the onset of labor through inhibition of PR function;Condon;Mol Endocrinol,2006
5. A decline in the levels of progesterone receptor coactivators in the pregnant uterus at term may antagonize progesterone receptor function and contribute to the initiation of parturition;Condon;Proc Natl Acad Sci USA,2003
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