Up-Regulation of the Progesterone Receptor (PR)-C Isoform in Laboring Myometrium by Activation of Nuclear Factor-κB May Contribute to the Onset of Labor through Inhibition of PR Function

Author:

Condon Jennifer C.1,Hardy Daniel B.1,Kovaric Kelly1,Mendelson Carole R.12

Affiliation:

1. Departments of Biochemistry (J.C.C., D.B.H., K.K., C.R.M.), Texas 75390-9038

2. Obstetrics and Gynecology (C.R.M.), North Texas March of Dimes Birth Defects Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Reference39 articles.

1. Increased expression of the rat myometrial oxytocin receptor messenger ribonucleic acid during labor requires both mechanical and hormonal signals.;Ou;Biol Reprod,1998

2. Regulation of transcripts encoding the myometrial gap junction protein, connexin-43, by estrogen and progesterone.;Petrocelli;Endocrinology,1993

3. Serum progesterone levels in the pregnant and postpartum laboratory mouse.;Virgo;Endocrinology,1974

4. Endocrine and paracrine regulation of birth at term and preterm.;Challis;Endocr Rev 2000,2000

5. The effects of an antiprogesterone steroid in women: interruption of the menstrual cycle and of early pregnancy.;Herrmann;C R Seances Acad Sci III,1982

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