Substituent effects on the ionization and partitioning of p-(aminoethyl)phenols and structurally related compounds: Electrostatic effects dependent on conformation-Reference-Cited by-同舟云学术

Substituent effects on the ionization and partitioning of p-(aminoethyl)phenols and structurally related compounds: Electrostatic effects dependent on conformation

Published:2009-12 Issue:12 Volume:98 Page:4534-4544
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Tejwani Ravindra W.,Stouch Terry R.,Anderson Bradley D.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference56 articles.

1. ADMET in silico modelling: Towards prediction paradise?;van de Waterbeemd;Nat Rev Drug Discov,2003

2. Advanced Chemistry Development/pKa dB, 10.0 edition,1994

3. Estimation of molecular linear free energy relationship descriptors by a group contribution approach. 2. Prediction of partition coefficients;Platts;J Chem Inf Comput Sci,2000

4. Prediction of pKa values for aliphatic carboxylic acids and alcohols with empirical atomic charge descriptors;Zhang;J Chem Inf Model,2006

5. pKa prediction for organic acids and bases;Perrin,1981

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