Dynamic, Nonsink Method for the Simultaneous Determination of Drug Permeability and Binding Coefficients in Liposomes
Author:
Affiliation:
1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, A323A ASTeCC Building, Lexington, Kentucky 40506, United States
Funder
National Cancer Institute
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/mp400765n
Reference38 articles.
1. Influence of Chain Ordering on the Selectivity of Dipalmitoylphosphatidylcholine Bilayer Membranes for Permeant Size and Shape
2. Liposomal drug transport: A molecular perspective from molecular dynamics simulations in lipid bilayers
3. Liposome Transport of Hydrophobic Drugs: Gel Phase Lipid Bilayer Permeability and Partitioning of the Lactone Form of a Hydrophobic Camptothecin, DB‐67
4. Determination of intraliposomal pH and its effect on membrane partitioning and passive loading of a hydrophobic camptothecin, DB-67
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