A Bayesian time‐to‐event pharmacokinetic model for phase I dose‐escalation trials with multiple schedules
Author:
Affiliation:
1. Department of Medical Statistics University Medical Center Göttingen Göttingen Germany
2. Advanced Exploratory Analytics Novartis Pharma AG Basel Switzerland
Publisher
Wiley
Subject
Statistics and Probability,Epidemiology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/sim.8703
Reference28 articles.
1. Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer
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3. Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials
4. Simultaneously optimizing dose and schedule of a new cytotoxic agent
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