Bispecific antibody process development: Assembly and purification of knob and hole bispecific antibodies
Author:
Affiliation:
1. Department of Purification Development; Genentech, Inc., 1 DNA Way; South San Francisco CA 94080
Publisher
Wiley
Subject
Biotechnology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/btpr.2590/fullpdf
Reference11 articles.
1. Preparation of bispecific antibodies by chemical recombination of monoclonal immunoglobulin G1 fragments;Brennan;Science.,1985
2. Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies;Schaefer;Proc Natl Acad Sci USA.,2011
3. The making of bispecific antibodies;Brinkmann;MAbs.,2017
4. Diabodies”: small bivalent and bispecific antibody fragments;Holliger;Proc Natl Acad Sci USA.,1993
5. A revival of bispecific antibodies;Kufer;Trends Biotechnol.,2004
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