Simultaneous determination of neochlorogenic acid, chlorogenic acid, cryptochlorogenic acid and geniposide in rat plasma by UPLC-MS/MS and its application to a pharmacokinetic study after administration of Reduning injection

Author:

Wang Yanjuan12,Wen Jing1,Zheng Weihua1,Zhao Longshan1ORCID,Fu Xiaohuan2,Wang Zhenzhong2,Xiong Zhili1,Li Famei1,Xiao Wei2

Affiliation:

1. School of Pharmacy; Shenyang Pharmaceutical University; 103 Wenhua Road Shenyang 110016 China

2. State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Processes; 58 Haichang South Road Xinpu District Lianyungang 222001 People's Republic of China

Funder

China the Postdoctoral Science Foundation

the PhD Start-up Research Fund of Liaoning Province

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference20 articles.

1. Pharmacokinetic study of Reduning Injection in rats;Bi;World Science and Technology - Modernization of Traditional Chinese Medicine and Materia Medica,2010

2. Simultaneous determination of organic acids and iridoid glycosides in traditional Chinese medicine (TCM) preparation reduning injection by rapid resolution liquid chromatography (RRLC) with ultraviolet (UV) detection under segmental monitoring mode;Chang;African Journal Pharmacy and Pharmacology,2013

3. On-line screening and identification of radical scavenging compounds extracted from Flos Lonicerae by LC-DAD-TOF-MS;Chen;Chromatographia,2008

4. Reduning injection for community-acquired pneumonia: meta-analysis;Gao;China Journal of Chinese Materia Medica,2011

5. Clinical observation of Reduning injection in treatment of patients with acute upper respiratory tract infections;Huang;Chinese Journal Clinical Pharmacolgy and Therapeutics,2006

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