Development and validation of amitriptyline and its metabolite in human plasma by ultra performance liquid chromatography-tandem mass spectrometry and its application to a bioequivalence study
Author:
Publisher
Wiley
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry
Reference19 articles.
1. Simultaneous high-performance liquid chromatographic determination of chlordiazepoxide and amitriptyline hydrochloride in two-component tablet formulations;Burke;Journal of Pharmaceutical Sciences,2006
2. Matrix effect in bio-analysis of illicit drugs with LC-MS/MS: influence of ionization type, sample preparation, and biofluid;Dams;Journal of the American Society for Mass Spectrometry,2003
3. Amitriptyline and nortriptyline serum determination by micellar liquid chromatography;Devasish;Journal of Pharmacological and Toxicological Methods,2005
4. Evaluation of ultra performance liquid chromatography Part I. Possibilities and limitations;De Villiers;Journal of Chromatography A,2006
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1. Method for the identification and quantification of sixty drugs and their metabolites in postmortem whole blood using liquid chromatography tandem mass spectrometry;Forensic Science International;2020-04
2. Practical liquid chromatography–tandem mass spectrometry method for the simultaneous quantification of amitriptyline, nortriptyline and their hydroxy metabolites in human serum;Biomedical Chromatography;2019-09-08
3. Quantitative Modeling Analysis Demonstrates the Impact of CYP2C19 and CYP2D6 Genetic Polymorphisms on the Pharmacokinetics of Amitriptyline and Its Metabolite, Nortriptyline;The Journal of Clinical Pharmacology;2018-11-19
4. Physiologically based pharmacokinetic-quantitative systems toxicology and safety (PBPK-QSTS) modeling approach applied to predict the variability of amitriptyline pharmacokinetics and cardiac safety in populations and in individuals;Journal of Pharmacokinetics and Pharmacodynamics;2018-06-25
5. Pharmacokinetic Variability of Drugs Used for Prophylactic Treatment of Migraine;CNS Drugs;2017-04-12
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