The use of image synthesis techniques in target and roi delineation in the upright position

Author:

Schreuder Andries Niek1ORCID,Paragios Nikos2,Kissick Michael1,Lis Michelle1,Underwood Tracy S. A.3,Mackie Rockwell3

Affiliation:

1. LEO Cancer care Middleton Wisconsin USA

2. TheraPanacea Paris France

3. Department of Medical Physics and Biomedical Engineering Leo Cancer Care London UK

Abstract

AbstractThe use of multi‐modality imaging technologies such as CT, MRI, and PET imaging is state of the art for radiation therapy treatment planning. Except for a limited number of low magnetic field MR scanners the majority of such imaging technologies can only image the patient in a recumbent position. Delivering radiation therapy treatments with the patient in an upright orientation has many benefits and several companies are now developing upright patient positioners combined with upright diagnostic helical CT scanners to facilitate upright radiation therapy treatments. Due to the directional changes in the gravitational forces on the patient's body, most structures and organs will change position and shape between the recumbent and upright positions. Detailed knowledge about such structures and organs are therefore often only available in the recumbent position. The problem statement is therefore well defined, that is, how do we know where such structures and organs, that is, the target or region at risk volumes, are in the upright position if those cannot be identified and or delineated accurately enough using the upright diagnostic quality CT images only? This paper outlines two methods based on synthetic CT or MR images to overcome this problem.

Publisher

Wiley

Subject

Radiology, Nuclear Medicine and imaging,Instrumentation,Radiation

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