Genotyping of a family with a novel deleteriousDPYDmutation supports the pretherapeutic screening of DPD deficiency with dihydrouracil/uracil ratio

Author:

Thomas F12,Hennebelle I12,Delmas C12,Lochon I12,Dhelens C3,Garnier Tixidre C4,Bonadona A5,Penel N6,Goncalves A7,Delord JP28,Toulas C9,Chatelut E12

Affiliation:

1. Institut Claudius Regaud, IUCT-O, Department of Pharmacology; Toulouse France

2. EA4553; Univ. Toulouse III Paul Sabatier; Toulouse France

3. UJF Grenoble I, University Hospital Albert Michallon, Department of Pharmacy; Grenoble France

4. Institut Daniel Hollard, Department of Medical Oncology; Grenoble France

5. University Hospital Albert Michallon, Medical Intensive Care Unit, UJF Grenoble I; Grenoble France

6. Centre Oscar Lambret, Department of Medical Oncology; Lille France

7. Institut Paoli Calmettes, Department of Medical Oncology; Marseille France

8. Institut Claudius Regaud, IUCT-O, Department of Medical Oncology; Toulouse France

9. Institut Claudius Regaud, IUCT-O, Laboratory of Oncogenetics; Toulouse France

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference50 articles.

1. Toxicity of fluorouracil in patients with advanced colorectal cancer: effect of administration schedule and prognostic factors;Meta-Analysis Group in Cancer;J. Clin. Oncol.,1998

2. Decreased dihydropyrimidine dehydrogenase activity in a population of patients with breast cancer: implication for 5-fluorouracil-based chemotherapy;Lu;Clin. Cancer Res.,1998

3. Population study of dihydropyrimidine dehydrogenase in cancer patients;Etienne;J. Clin. Oncol.,1994

4. Dihydropyrimidine dehydrogenase and the efficacy and toxicity of 5-fluorouracil;Kuilenburg;Eur. J. Cancer,2004

5. Relationship between single nucleotide polymorphisms and haplotypes in DPYD and toxicity and efficacy of capecitabine in advanced colorectal cancer;Deenen;Clin. Cancer Res.,2011

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3