Comparative Assessment of In Vitro–In Vivo Extrapolation Methods used for Predicting Hepatic Metabolic Clearance of Drugs-Reference-Cited by-同舟云学术

Comparative Assessment of In Vitro–In Vivo Extrapolation Methods used for Predicting Hepatic Metabolic Clearance of Drugs

Published:2012-11 Issue:11 Volume:101 Page:4308-4326
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Poulin Patrick,Hop Cornelis E.C.A.,Ho Quynh,Halladay Jason S.,Haddad Sami,Kenny Jane R.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference47 articles.

1. Impact of input parameters on the prediction of hepatic plasma clearance using the well-stirred model;Wan;Curr Drug Metab,2010

2. Prediction of human clearance of twenty-nine drugs from hepatic microsomal intrinsic clearance data: An examination of in vitro half-life approach and nonspecific binding to microsomes;Obach;Drug Metab Dispos,1999

3. Substrate depletion approach for determining in vitro metabolic clearance: Time dependencies in hepatocyte and microsomal incubations;Jones;Drug Metab Dispos,2004

4. Prediction of human pharmacokinetics using physiologically-based pharmacokinetics modeling: A retrospective analysis of 26 clinically tested drugs;De;Drug Metab Dispos,2007

5. Prediction of human pharmacokinetics from preclinical information: Comparative accuracy of quantitative prediction approaches;Hosea;J Clin Pharm,2009

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