Prediction of Human Pharmacokinetics Using Physiologically Based Modeling: A Retrospective Analysis of 26 Clinically Tested Drugs-Reference-Cited by-同舟云学术

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Prediction of Human Pharmacokinetics Using Physiologically Based Modeling: A Retrospective Analysis of 26 Clinically Tested Drugs

Published:2007-07-09 Issue:10 Volume:35 Page:1766-1780
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

De Buck Stefan S.,Sinha Vikash K.,Fenu Luca A.,Nijsen Marjoleen J.,Mackie Claire E.,Gilissen Ron A. H. J.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference38 articles.

1. Predicting the impact of physiological and biochemical processes on oral drug bioavailability

2. The Influence of Nonspecific Microsomal Binding on Apparent Intrinsic Clearance, and Its Prediction from Physicochemical Properties

3. Physiological pharmacokinetics

4. Prediction of the volume of distribution of a drug: which tissue-plasma partition coefficients are needed?

5. The Prediction of Drug Metabolism, Tissue Distribution, and Bioavailability of 50 Structurally Diverse Compounds in Rat Using Mechanism-Based Absorption, Distribution, and Metabolism Prediction Tools

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