Synthesis of14C-labeled piperidines and application to synthesis of [14C]SCH 351125, a CCR5 receptor antagonist-Reference-Cited by-同舟云学术

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Synthesis of14C-labeled piperidines and application to synthesis of [14C]SCH 351125, a CCR5 receptor antagonist

Published:2007 Issue:7 Volume:50 Page:643-648
ISSN:0362-4803
Container-title:Journal of Labelled Compounds and Radiopharmaceuticals
language:en
Short-container-title:J Label Compd Radiopharm

Author:

Ren Sumei,McNamara Paul,Royster Pernilla,Lee Jae,Saluja Surinderjit S.,Koharski David,Hendershot Sharon,Truong Van

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology, Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Reference10 articles.

1. Discovery of 4-[(Z)-(4-Bromophenyl)- (ethoxyimino)methyl]-1‘-[(2,4-dimethyl-3- pyridinyl)carbonyl]-4‘-methyl-1,4‘- bipiperidine N-Oxide (SCH 351125): An Orally Bioavailable Human CCR5 Antagonist for the Treatment of HIV Infection

2. , , , , , . (Schering Corporation), WO 03/033490 A1, April 2003.

3. SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo

4. Synthesis, SAR, and Biological Evaluation of Oximino-Piperidino-Piperidine Amides. 1. Orally Bioavailable CCR5 Receptor Antagonists with Potent Anti-HIV Activity

5. Reactions of allylsilanes with simple iminium salts in water: A facile route to piperidines via a aminomethano desilylation-cyclization process

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1. Classical and Modern Methods for Carbon Isotope Labeling;MOROC J CHEM;2024

2. Creation of a nitrosamine library labelled with 14C or tritium;Journal of Radioanalytical and Nuclear Chemistry;2023-01-20

3. Synthesis of3H,2H4and14C-SCH 417690 (Vicriviroc);Journal of Labelled Compounds and Radiopharmaceuticals;2016-03-14

4. Radiochemistry;Annual Reports Section "A" (Inorganic Chemistry);2008

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