Synthesis of3H,2H4and14C-SCH 417690 (Vicriviroc)-Reference-Cited by-同舟云学术

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Synthesis of3H,2H4and14C-SCH 417690 (Vicriviroc)

Published:2016-03-14 Issue:5 Volume:59 Page:190-196
ISSN:0362-4803
Container-title:Journal of Labelled Compounds and Radiopharmaceuticals
language:en
Short-container-title:J. Label Compd. Radiopharm

Author:

Hesk D.¹,Borges S.¹,Hendershot S.¹,Koharski D.¹,McNamara P.¹,Ren S.¹,Saluja S.¹,Truong V.¹,Voronin K.¹

Affiliation:

1. Merck and Co; 126 E. Lincoln Avenue, RY 80R Rahway NJ 07065 USA

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology, Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jlcr.3387/fullpdf

Reference15 articles.

1. Piperazine-Based CCR5 Antagonists as HIV-1 Inhibitors. IV. Discovery of 1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]- 4-[4-{2-methoxy-1(R)-4-(trifluoromethyl)phenyl}ethyl-3(S)-methyl-1-piperazinyl]- 4-methylpiperidine (Sch-417690/Sch-D), a Potent, Highly Selective, and Orally Bioavailable CCR5 Antagonist

2. Chemokine Receptors As HIV Co-Receptors: Targets for Therapeutic Intervention in AIDS

3. Recent progress in discovery of small-molecule CCR5 chemokine receptor ligands as HIV-1 inhibitors

4. Discovery of 4-[(Z)-(4-Bromophenyl)- (ethoxyimino)methyl]-1‘-[(2,4-dimethyl-3- pyridinyl)carbonyl]-4‘-methyl-1,4‘- bipiperidine N-Oxide (SCH 351125): An Orally Bioavailable Human CCR5 Antagonist for the Treatment of HIV Infection

5. Highly enantioselective borane reduction of ketones catalyzed by chiral oxazaborolidines. Mechanism and synthetic implications

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Incorporation of Hydrogen Isotopes into Biologically Active Compounds;Radiochemistry;2022-08

2. Automated radiosynthesis of the adenosine A _2A receptor‐targeting radiotracer [ ¹⁸ F]FLUDA;Journal of Labelled Compounds and Radiopharmaceuticals;2022-03-24

3. Synthesis of 3 H, 13 C2 , 2 H4 14 C-SCH 430765 and 35 S-SCH 500946, potent and selective inhibitors of the NPY5 receptor;Journal of Labelled Compounds and Radiopharmaceuticals;2018-04-15

4. Efficient Brønsted-Acid-Catalyzed Deuteration of Arenes and Their Transformation to Functionalized Deuterated Products;Asian Journal of Organic Chemistry;2017-06-29

5. Synthesis of3H,2H4, and14C-MK 3814 (preladenant);Journal of Labelled Compounds and Radiopharmaceuticals;2017-03-17

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