The transcriptional regulator NAB2 reveals a two-step induction of TRAIL in activated plasmacytoid DCs

Author:

Balzarolo Melania12,Karrich Julien J.3,Engels Sander2,Blom Bianca3,Medema Jan Paul1,Wolkers Monika C.12

Affiliation:

1. Laboratory of Experimental Oncology and Radiobiology (LEXOR); Center for Experimental Molecular Medicine (CEMM); Academic Medical Center (AMC); University of Amsterdam; Amsterdam the Netherlands

2. Department of Hematopoiesis, Sanquin Research-AMC Landsteiner Laboratory; Amsterdam the Netherlands

3. Department of Cell Biology & Histology; Academic Medical Center (AMC); University of Amsterdam; Amsterdam the Netherlands

Funder

Dutch Science Foundation

VIDI

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference39 articles.

1. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon;Cella;Nat. Med.,1999

2. Type I interferons in host defence;Stetson;Immunity,2006

3. Interferons, interferon-like cytokines, and their receptors;Petska;Immunol. Rev.,2004

4. HIV-1 immunopathogenesis: how good interferon turns bad;Herbeuval;Clin. Immunol.,2007

5. Virus or TLR agonists induce TRAIL-mediated cytotoxic activity of plasmacytoid dendritic cells;Chaperot;J. Immunol.,2006

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