Maternal ω3 docosapentaenoic acid inhibits infant allergic dermatitis through TRAIL‐expressing plasmacytoid dendritic cells in mice

Author:

Hirata So‐ichiro12ORCID,Nagatake Takahiro1,Sawane Kento134,Hosomi Koji1,Honda Tetsuya5,Ono Sachiko5,Shibuya Noriko6,Saito Emiko7,Adachi Jun8,Abe Yuichi8,Isoyama Junko8,Suzuki Hidehiko1,Matsunaga Ayu1,Tomonaga Takeshi8,Kiyono Hiroshi9101112,Kabashima Kenji5,Arita Makoto131415ORCID,Kunisawa Jun124916ORCID

Affiliation:

1. Laboratory of Vaccine Materials Center for Vaccine and Adjuvant Research, and Laboratory of Gut Environmental System National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) Ibaraki‐city Japan

2. Department of Microbiology and Immunology Kobe University Graduate School of Medicine Kobe‐city Japan

3. Nippon Flour Mills Co., Ltd., Innovation Center Atsugi‐city Japan

4. Graduate School of Pharmaceutical Sciences Osaka University Suita‐city Japan

5. Department of Dermatology Kyoto University Graduate School of Medicine Kyoto‐city Japan

6. Department of Pediatrics Maternal & Child Health Center, Aiiku Clinic Tokyo Japan

7. Department of Human Nutrition Tokyo Kasei Gakuin University Tokyo Japan

8. Laboratory of Proteome Research National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) Ibaraki‐city Japan

9. International Research and Development Center for Mucosal Vaccines The Institute of Medical ScienceThe University of Tokyo Tokyo Japan

10. Division of Gastroenterology Department of Medicine University of California San Diego (UCSD) San Diego CA USA

11. Chiba University (CU)‐UCSD Center for Mucosal Immunology, Allergy and Vaccines (cMAV) UCSD San Diego CA USA

12. Department of Immunology Graduate School of Medicine Chiba University Chiba‐city Japan

13. Laboratory for Metabolomics RIKEN Center for Integrative Medical Sciences Yokohama‐city Japan

14. Division of Physiological Chemistry and Metabolism Graduate School of Pharmaceutical Sciences Keio University Tokyo Japan

15. Graduate School of Medical Life Science Yokohama City University Yokohama‐city Japan

16. Graduate School of Medicine and Graduate School of Dentistry Osaka University Suita‐city Japan

Funder

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Astellas Foundation for Research on Metabolic Disorders

Ono Medical Research Foundation

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

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