Radiosynthesis of novel pitavastatin derivative ([18F]PTV-F1) as a tracer for hepatic OATP using a one-pot synthetic procedure

Author:

Kimura Hiroyuki12,Yagi Yusuke1,Arimitsu Kenji12,Maeda Kazuya3,Ikejiri Kazuaki3,Takano Jun-ichi3,Kusuhara Hiroyuki3,Kagawa Shinya4,Ono Masahiro1,Sugiyama Yuichi5,Saji Hideo1

Affiliation:

1. Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences; Kyoto University; Sakyo-ku Kyoto Japan

2. Department of Analytical and Bioinorganic Chemistry; Kyoto Pharmaceutical University; Misasagi, Yamashina-ku Kyoto Japan

3. Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences; The University of Tokyo; Bunkyo-ku Tokyo Japan

4. Shiga Medical Center Research Institute; Moriyama, Moriyama City Shiga Japan

5. Sugiyama Laboratory, RIKEN Innovation Center; RIKEN Cluster for Industry Partnerships, RIKEN; Tsurumi-ku Yokohama Japan

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology, Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Reference18 articles.

1. A novel human hepatic organic anion transporting polypeptide (OATP2);Hsiang;Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters. J Biol Chem,1999

2. Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide;König;J Biol Chem,2000

3. Impact of genetic polymorphisms of transporters on the pharmacokinetic, pharmacodynamic and toxicological properties of anionic drugs;Maeda;Drug Metab Dispos,2008

4. Evaluation of drug-drug interaction in the hepatobiliary and renal transport of drugs;Shitara;Annu Rev Pharmacol Toxicol,2005

5. Positron emission tomography studies using (15R)-16-m-[11C]tolyl-17,18,19,20-tetranorisocarbacyclin methyl ester for the evaluation of hepatobiliary transport;Takashima;J Pharmacol Exp Ther,2010

Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3