Differentiation of cyclosporin A from isocyclosporin A by liquid chromatography/electrospray ionization mass spectrometry with post-column addition of divalent metal salt

Author:

Cirigliano Adriana M.1,Cabrera Gabriela M.1

Affiliation:

1. Departamento de Química Orgánica, UMyMFOR-CONICET, Facultad de Ciencias Exactas y Naturales; Universidad de Buenos Aires; Ciudad Universitaria, Pabellón II, 3° piso C1428EHA Buenos Aires Argentina

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Analytical Chemistry

Reference20 articles.

1. Cyclosporin A - a review on fermentative production, downstream processing and pharmacological applications;Survase;Biotechnol. Adv.,2011

2. The panorama of cyclosporin research;Balakrishnan;Basic Microbiol.,1996

3. Cyclosporin A, FK506 and rapamycin: more than just immunosuppression;Kunz;Trends Biochem. Sci.,1993

4. Pharmacology of cyclosporine (sandimmune). IV. Pharmacological properties in vivo;Borel;Pharmacol. Rev.,1990

5. 1H NMR analysis of isocyclosporin a prepared in organic solvent and in aqueous solution;Arnoldi;Bioorg. Chem.,1997

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