A weighted method for estimation of receptor occupancy for pharmacodynamic measurements in drug development-Reference-Cited by-同舟云学术

A weighted method for estimation of receptor occupancy for pharmacodynamic measurements in drug development

Author:

Sternebring Ola¹,Alifrangis Lene¹,Christensen Toke Folke²,Ji Hong³,Hegelund Anne Charlotte⁴,Högerkorp Carl-Magnus³

Affiliation:

1. Department of Development DMPK; Novo Nordisk A/S; DK-2760 Maaloev Denmark

2. Department of Quantitative Clinical Pharmacology; Novo Nordisk A/S; DK-2860 Soeborg Denmark

3. Department of Pharmacodynamics; Novo Nordisk A/S; DK-2760 Maaloev Denmark

4. Department of Development Bioanalysis; Novo Nordisk A/S; DK-2760 Maaloev Denmark

Publisher

Wiley

Subject

Cell Biology,Histology,Pathology and Forensic Medicine

Link

Reference38 articles.

2. Overview of flow cytometry receptor occupancy assays and their utility in drug development;Stewart;Cytom Part B Clin Cytom

3. Recommendations for the development and validation of flow cytometry-based receptor occupancy assays;Green;Cytom Part B Clin Cytom

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