Receptor occupancy assessment and interpretation in terms of quantitative systems pharmacology: nivolumab case study
Author:
Affiliation:
1. InSysBio UK Limited, Edinburgh, UK
Funder
The author(s) reported there is no funding associated with the work featured in this article
Publisher
Informa UK Limited
Subject
Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2022.2156317
Reference35 articles.
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4. Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation
5. SHP-1 and SHP-2 Associate with Immunoreceptor Tyrosine-Based Switch Motif of Programmed Death 1 upon Primary Human T Cell Stimulation, but Only Receptor Ligation Prevents T Cell Activation
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