Overcoming the Lack of Oral Availability of Cyclic Hexapeptides: Design of a Selective and Orally Available Ligand for the Integrin αvβ3-Reference-Cited by-同舟云学术

Overcoming the Lack of Oral Availability of Cyclic Hexapeptides: Design of a Selective and Orally Available Ligand for the Integrin αvβ3

Published:2017-11-23 Issue:51 Volume:56 Page:16405-16409
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Weinmüller Michael¹,Rechenmacher Florian¹,Kiran Marelli Udaya²,Reichart Florian¹,Kapp Tobias G.¹,Räder Andreas F. B.¹,Di Leva Francesco Saverio³,Marinelli Luciana³,Novellino Ettore³,Muñoz-Félix José M.⁴,Hodivala-Dilke Kairbaan⁴,Schumacher Adi⁵,Fanous Joseph⁵,Gilon Chaim⁵,Hoffman Amnon⁵,Kessler Horst¹^ORCID

Affiliation:

1. Institute for Advanced Study and Center of Integrated Protein Science; Department Chemie; Technische Universität München; Lichtenbergstrasse 4 85748 Garching Germany

2. Central NMR Facility and Division of Organic Chemistry; CSIR-National Chemical Laboratory; Pune India

3. Dipartimento di Farmacia; Università di Napoli Federico II; Napoli Italy

4. Centre for Tumour Biology; Barts Cancer Institute, -; Queen Mary University of London; John Vane Science Centre; Londonn UK

5. Institutes of Chemistry and Drug Research; The Hebrew University of Jerusalem; Israel

Funder

Deutsche Forschungsgemeinschaft

Worldwide Cancer Research

Cancer Research UK

MIUR-PRIN 2015

Publisher

Wiley

Subject