N-Methylated Cyclic RGD Peptides as Highly Active and Selective αVβ3 Integrin Antagonists
Author:
Affiliation:
1. Institut für Organische Chemie und Biochemie, Technische Universität München, Lichtenbergstrasse 4, D-85747 Garching, Germany, and Merck KGaA Preclinical Research, Frankfurter Strasse 250, D-64271 Darmstadt, Germany
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm970832g
Reference60 articles.
1. Arg-Gly-Asp constrained within cyclic pentapoptides Strong and selective inhibitors of cell adhesion to vitronectin and laminin fragment P1
2. Conformation/activity studies of rationally designed potent anti-adhesive RGD peptides
3. Selective Inhibition of Trypanosomal Triosephosphate Isomerase by a Thiopeptide
4. Conformation of cyclic peptides. Principle concepts and the design of selectivity and superactivity in bioactive sequences by 'spatial screening'
5. Design of superactive and selective integrin receptor antagonists containing the RGD sequence
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