Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation-Reference-Cited by-同舟云学术

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Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation

Published:2012-05-08 Issue:25 Volume:51 Page:6140-6143
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Sun Qi,Burke Jason P.,Phan Jason,Burns Michael C.,Olejniczak Edward T.,Waterson Alex G.,Lee Taekyu,Rossanese Olivia W.,Fesik Stephen W.

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/anie.201201358/fullpdf

Reference21 articles.

1. Hallmarks of Cancer: The Next Generation

2. RAS oncogenes: weaving a tumorigenic web

3. Common occurrence of multiple K-RAS mutations in pancreatic cancers with associated precursor lesions and in biliary cancers

4. Non-redundancy within the RAS oncogene family: Insights into mutational disparities in cancer

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1. Surface-mutagenesis strategies to enable structural biology crystallization platforms;Acta Crystallographica Section D Structural Biology;2024-08-29

2. Identification and Characterization of Novel Small-Molecule Enhancers of the CUL3^LZTR1 E3 Ligase KRAS Complex;ACS Chemical Biology;2024-08-28

3. Mapping protein binding sites by photoreactive fragment pharmacophores;Communications Chemistry;2024-07-31

4. Direct RAS inhibitors turn 10;Nature Chemical Biology;2024-07-26

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